Unsolved Mysteries explores unsolved cases in which you, the viewer, can call in or write and solve them. The show looks at cases such as: lost loves, missing persons, homicide, supernatural, the unexplained, wanted, etc. Unsolved Mysteries usually has four segments in one show, and sometimes shows updates. Unsolved Mysteries has solved 40% of their featured cases, that is 300 cases solved out of about 1,200.
Host Robert Stack presides over an investigation into unsolved mysteries ranging from murders to UFO sightings. Through reenactments and interviews, viewers are presented with the known facts of each case. Anyone with additional information is then urged to contact the show's producers via a toll-free telephone number.